Y-27632 Dihydrochloride CAS #129830-38-2 is an ATP-competitive inhibitor of ROCKs including pl60ROCK (Ki = 140nM) and ROCK-11 (IC50 = 800 nM). At a concentration of 10µM, Y-27632 blocks apoptosis of dissociated cultured human embryonic stem cells, increasing cloning efficiency by 25% and sustaining survival up to 30 passages. Manufactured to meet an ultra-pure standard greater than 99%.
Name : Y-27632 Dihydrochloride
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High standard > 99%
C14H21N3O.2HCL
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Specifications (Click here):
Y-27632 Dihydrochloride, 99% Ultra-pure
Specifications
Product:
Y-27632 (2HCL)
Catalog number:
BT-2017-001
CAS number:
129830-38-2
Structure:
Molecular formula:
C14H21N3O.2HCL
Molecular weight:
320.25
Appearance:
Crystalline powder, off-white
Purity: (%)
≥ 99+ (HLPC)
Solubility:
Completely soluble in MeOH & H2O, DMSO and Ethanol
NMR Spectrum:
Conforms to structure
Storage:
Stable at -20ºC for 3 years
Toxicity:
Unknown, avoid exposure
Synonyms
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide di-hydrochloride, ROCK inhibitor Y-27632
